肿瘤分割是放疗治疗计划的基本步骤。为了确定口咽癌患者（OPC）原发性肿瘤（GTVP）的准确分割，需要同时评估不同图像模态，并从不同方向探索每个图像体积。此外，分割的手动固定边界忽略了肿瘤描述中已知的空间不确定性。这项研究提出了一种新型的自动深度学习（DL）模型，以在注册的FDG PET/CT图像上进行逐片自适应GTVP分割的辐射肿瘤学家。我们包括138名在我们研究所接受过（化学）辐射治疗的OPC患者。我们的DL框架利用了间和板板的上下文。连续3片的串联FDG PET/CT图像和GTVP轮廓的序列用作输入。进行了3倍的交叉验证，进行了3​​次，对从113例患者的轴向（a），矢状（s）和冠状（c）平面提取的序列进行了训练。由于体积中的连续序列包含重叠的切片，因此每个切片产生了平均的三个结果预测。在A，S和C平面中，输出显示具有预测肿瘤的概率不同的区域。使用平均骰子得分系数（DSC）评估了25名患者的模型性能。预测是最接近地面真理的概率阈值（在A中为0.70，s为0.70，在s中为0.77，在C平面中为0.80）。提出的DL模型的有希望的结果表明，注册的FDG PET/CT图像上的概率图可以指导逐片自适应GTVP分割中的辐射肿瘤学家。

在2015年和2019年之间，地平线的成员2020年资助的创新培训网络名为“Amva4newphysics”，研究了高能量物理问题的先进多变量分析方法和统计学习工具的定制和应用，并开发了完全新的。其中许多方法已成功地用于提高Cern大型Hadron撞机的地图集和CMS实验所执行的数据分析的敏感性;其他几个人，仍然在测试阶段，承诺进一步提高基本物理参数测量的精确度以及新现象的搜索范围。在本文中，在研究和开发的那些中，最相关的新工具以及对其性能的评估。

Advances in computer vision and machine learning techniques have led to significant development in 2D and 3D human pose estimation from RGB cameras, LiDAR, and radars. However, human pose estimation from images is adversely affected by occlusion and lighting, which are common in many scenarios of interest. Radar and LiDAR technologies, on the other hand, need specialized hardware that is expensive and power-intensive. Furthermore, placing these sensors in non-public areas raises significant privacy concerns. To address these limitations, recent research has explored the use of WiFi antennas (1D sensors) for body segmentation and key-point body detection. This paper further expands on the use of the WiFi signal in combination with deep learning architectures, commonly used in computer vision, to estimate dense human pose correspondence. We developed a deep neural network that maps the phase and amplitude of WiFi signals to UV coordinates within 24 human regions. The results of the study reveal that our model can estimate the dense pose of multiple subjects, with comparable performance to image-based approaches, by utilizing WiFi signals as the only input. This paves the way for low-cost, broadly accessible, and privacy-preserving algorithms for human sensing.

Due to the environmental impacts caused by the construction industry, repurposing existing buildings and making them more energy-efficient has become a high-priority issue. However, a legitimate concern of land developers is associated with the buildings' state of conservation. For that reason, infrared thermography has been used as a powerful tool to characterize these buildings' state of conservation by detecting pathologies, such as cracks and humidity. Thermal cameras detect the radiation emitted by any material and translate it into temperature-color-coded images. Abnormal temperature changes may indicate the presence of pathologies, however, reading thermal images might not be quite simple. This research project aims to combine infrared thermography and machine learning (ML) to help stakeholders determine the viability of reusing existing buildings by identifying their pathologies and defects more efficiently and accurately. In this particular phase of this research project, we've used an image classification machine learning model of Convolutional Neural Networks (DCNN) to differentiate three levels of cracks in one particular building. The model's accuracy was compared between the MSX and thermal images acquired from two distinct thermal cameras and fused images (formed through multisource information) to test the influence of the input data and network on the detection results.

The advances in Artificial Intelligence are creating new opportunities to improve lives of people around the world, from business to healthcare, from lifestyle to education. For example, some systems profile the users using their demographic and behavioral characteristics to make certain domain-specific predictions. Often, such predictions impact the life of the user directly or indirectly (e.g., loan disbursement, determining insurance coverage, shortlisting applications, etc.). As a result, the concerns over such AI-enabled systems are also increasing. To address these concerns, such systems are mandated to be responsible i.e., transparent, fair, and explainable to developers and end-users. In this paper, we present ComplAI, a unique framework to enable, observe, analyze and quantify explainability, robustness, performance, fairness, and model behavior in drift scenarios, and to provide a single Trust Factor that evaluates different supervised Machine Learning models not just from their ability to make correct predictions but from overall responsibility perspective. The framework helps users to (a) connect their models and enable explanations, (b) assess and visualize different aspects of the model, such as robustness, drift susceptibility, and fairness, and (c) compare different models (from different model families or obtained through different hyperparameter settings) from an overall perspective thereby facilitating actionable recourse for improvement of the models. It is model agnostic and works with different supervised machine learning scenarios (i.e., Binary Classification, Multi-class Classification, and Regression) and frameworks. It can be seamlessly integrated with any ML life-cycle framework. Thus, this already deployed framework aims to unify critical aspects of Responsible AI systems for regulating the development process of such real systems.

Model calibration, which is concerned with how frequently the model predicts correctly, not only plays a vital part in statistical model design, but also has substantial practical applications, such as optimal decision-making in the real world. However, it has been discovered that modern deep neural networks are generally poorly calibrated due to the overestimation (or underestimation) of predictive confidence, which is closely related to overfitting. In this paper, we propose Annealing Double-Head, a simple-to-implement but highly effective architecture for calibrating the DNN during training. To be precise, we construct an additional calibration head-a shallow neural network that typically has one latent layer-on top of the last latent layer in the normal model to map the logits to the aligned confidence. Furthermore, a simple Annealing technique that dynamically scales the logits by calibration head in training procedure is developed to improve its performance. Under both the in-distribution and distributional shift circumstances, we exhaustively evaluate our Annealing Double-Head architecture on multiple pairs of contemporary DNN architectures and vision and speech datasets. We demonstrate that our method achieves state-of-the-art model calibration performance without post-processing while simultaneously providing comparable predictive accuracy in comparison to other recently proposed calibration methods on a range of learning tasks.

Dataset scaling, also known as normalization, is an essential preprocessing step in a machine learning pipeline. It is aimed at adjusting attributes scales in a way that they all vary within the same range. This transformation is known to improve the performance of classification models, but there are several scaling techniques to choose from, and this choice is not generally done carefully. In this paper, we execute a broad experiment comparing the impact of 5 scaling techniques on the performances of 20 classification algorithms among monolithic and ensemble models, applying them to 82 publicly available datasets with varying imbalance ratios. Results show that the choice of scaling technique matters for classification performance, and the performance difference between the best and the worst scaling technique is relevant and statistically significant in most cases. They also indicate that choosing an inadequate technique can be more detrimental to classification performance than not scaling the data at all. We also show how the performance variation of an ensemble model, considering different scaling techniques, tends to be dictated by that of its base model. Finally, we discuss the relationship between a model's sensitivity to the choice of scaling technique and its performance and provide insights into its applicability on different model deployment scenarios. Full results and source code for the experiments in this paper are available in a GitHub repository.\footnote{https://github.com/amorimlb/scaling\_matters}

Over the past decade, neural networks have been successful at making predictions from biological sequences, especially in the context of regulatory genomics. As in other fields of deep learning, tools have been devised to extract features such as sequence motifs that can explain the predictions made by a trained network. Here we intend to go beyond explainable machine learning and introduce SEISM, a selective inference procedure to test the association between these extracted features and the predicted phenotype. In particular, we discuss how training a one-layer convolutional network is formally equivalent to selecting motifs maximizing some association score. We adapt existing sampling-based selective inference procedures by quantizing this selection over an infinite set to a large but finite grid. Finally, we show that sampling under a specific choice of parameters is sufficient to characterize the composite null hypothesis typically used for selective inference-a result that goes well beyond our particular framework. We illustrate the behavior of our method in terms of calibration, power and speed and discuss its power/speed trade-off with a simpler data-split strategy. SEISM paves the way to an easier analysis of neural networks used in regulatory genomics, and to more powerful methods for genome wide association studies (GWAS).

The Elo algorithm, due to its simplicity, is widely used for rating in sports competitions as well as in other applications where the rating/ranking is a useful tool for predicting future results. However, despite its widespread use, a detailed understanding of the convergence properties of the Elo algorithm is still lacking. Aiming to fill this gap, this paper presents a comprehensive (stochastic) analysis of the Elo algorithm, considering round-robin (one-on-one) competitions. Specifically, analytical expressions are derived characterizing the behavior/evolution of the skills and of important performance metrics. Then, taking into account the relationship between the behavior of the algorithm and the step-size value, which is a hyperparameter that can be controlled, some design guidelines as well as discussions about the performance of the algorithm are provided. To illustrate the applicability of the theoretical findings, experimental results are shown, corroborating the very good match between analytical predictions and those obtained from the algorithm using real-world data (from the Italian SuperLega, Volleyball League).

Digital platforms, including online forums and helplines, have emerged as avenues of support for caregivers suffering from postpartum mental health distress. Understanding support seekers' experiences as shared on these platforms could provide crucial insight into caregivers' needs during this vulnerable time. In the current work, we provide a descriptive analysis of the concerns, psychological states, and motivations shared by healthy and distressed postpartum support seekers on two digital platforms, a one-on-one digital helpline and a publicly available online forum. Using a combination of human annotations, dictionary models and unsupervised techniques, we find stark differences between the experiences of distressed and healthy mothers. Distressed mothers described interpersonal problems and a lack of support, with 8.60% - 14.56% reporting severe symptoms including suicidal ideation. In contrast, the majority of healthy mothers described childcare issues, such as questions about breastfeeding or sleeping, and reported no severe mental health concerns. Across the two digital platforms, we found that distressed mothers shared similar content. However, the patterns of speech and affect shared by distressed mothers differed between the helpline vs. the online forum, suggesting the design of these platforms may shape meaningful measures of their support-seeking experiences. Our results provide new insight into the experiences of caregivers suffering from postpartum mental health distress. We conclude by discussing methodological considerations for understanding content shared by support seekers and design considerations for the next generation of support tools for postpartum parents.